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Axial contraction and short-range compaction of chromatin synergistically promote mitotic chromosome condensation
The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units of manageable size for the mitotic spindle. Here, we report on how phosphorylation at serine 10 of histone H3 (H3 S10) contributes to this process. Using a fluorescence-based assay to study local com...
Autores principales: | Kruitwagen, Tom, Denoth-Lippuner, Annina, Wilkins, Bryan J, Neumann, Heinz, Barral, Yves |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755758/ https://www.ncbi.nlm.nih.gov/pubmed/26615018 http://dx.doi.org/10.7554/eLife.10396 |
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