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A Septin Requirement Differentiates Autonomous- and Contact-Facilitated T Cell Proliferation
T cell proliferation is initiated by T cell antigen receptor (TCR) triggering and/or by soluble growth factors. In characterizing T cells lacking the septin cytoskeleton, we found that successful cell division has discrete septin-dependent and -independent pathways. Septin-deficient T cells failed c...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755847/ https://www.ncbi.nlm.nih.gov/pubmed/26692174 http://dx.doi.org/10.1038/ni.3330 |