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Impact of clinically tested NEP/ACE inhibitors on tumor uptake of [(111)In-DOTA]MG11—first estimates for clinical translation
BACKGROUND: We have recently shown that treatment of mice with the neutral endopeptidase (NEP) inhibitor phosphoramidon (PA) improves the bioavailability and tumor uptake of biodegradable radiopeptides. For the truncated gastrin radiotracer [(111)In-DOTA]MG11 ([(DOTA)DGlu(10)]gastrin(10–17)), this m...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755954/ https://www.ncbi.nlm.nih.gov/pubmed/26882895 http://dx.doi.org/10.1186/s13550-015-0158-3 |