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Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective
Hepatocellular carcinoma (HCC) ranks second amongst all causes of cancer deaths globally. It is on a rise in Pakistan and might represent the most common cancer in adult males. Pakistan contributes significantly to global burden of hepatitis C, which is a known risk factor for HCC, and has one of th...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756136/ https://www.ncbi.nlm.nih.gov/pubmed/26955390 http://dx.doi.org/10.1155/2016/5942306 |
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author | Hafeez Bhatti, Abu Bakar Dar, Faisal Saud Waheed, Anum Shafique, Kashif Sultan, Faisal Shah, Najmul Hassan |
author_facet | Hafeez Bhatti, Abu Bakar Dar, Faisal Saud Waheed, Anum Shafique, Kashif Sultan, Faisal Shah, Najmul Hassan |
author_sort | Hafeez Bhatti, Abu Bakar |
collection | PubMed |
description | Hepatocellular carcinoma (HCC) ranks second amongst all causes of cancer deaths globally. It is on a rise in Pakistan and might represent the most common cancer in adult males. Pakistan contributes significantly to global burden of hepatitis C, which is a known risk factor for HCC, and has one of the highest prevalence rates (>3%) in the world. In the absence of a national cancer registry and screening programs, prevalence of hepatitis and HCC only represents estimates of the real magnitude of this problem. In this review, we present various aspects of HCC in Pakistan, comparing and contrasting it with the global trends in cancer care. There is a general lack of awareness regarding risk factors of HCC in Pakistani population and prevalence of hepatitis C has increased. In addition, less common risk factors are also on a rise. Majority of patients present with advanced HCC and are not eligible for definitive treatment. We have attempted to highlight issues that have a significant bearing on HCC outcome in Pakistan. A set of strategies have been put forth that can potentially help reduce incidence and improve HCC outcome on national level. |
format | Online Article Text |
id | pubmed-4756136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-47561362016-03-07 Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective Hafeez Bhatti, Abu Bakar Dar, Faisal Saud Waheed, Anum Shafique, Kashif Sultan, Faisal Shah, Najmul Hassan Gastroenterol Res Pract Review Article Hepatocellular carcinoma (HCC) ranks second amongst all causes of cancer deaths globally. It is on a rise in Pakistan and might represent the most common cancer in adult males. Pakistan contributes significantly to global burden of hepatitis C, which is a known risk factor for HCC, and has one of the highest prevalence rates (>3%) in the world. In the absence of a national cancer registry and screening programs, prevalence of hepatitis and HCC only represents estimates of the real magnitude of this problem. In this review, we present various aspects of HCC in Pakistan, comparing and contrasting it with the global trends in cancer care. There is a general lack of awareness regarding risk factors of HCC in Pakistani population and prevalence of hepatitis C has increased. In addition, less common risk factors are also on a rise. Majority of patients present with advanced HCC and are not eligible for definitive treatment. We have attempted to highlight issues that have a significant bearing on HCC outcome in Pakistan. A set of strategies have been put forth that can potentially help reduce incidence and improve HCC outcome on national level. Hindawi Publishing Corporation 2016 2016-02-03 /pmc/articles/PMC4756136/ /pubmed/26955390 http://dx.doi.org/10.1155/2016/5942306 Text en Copyright © 2016 Abu Bakar Hafeez Bhatti et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Hafeez Bhatti, Abu Bakar Dar, Faisal Saud Waheed, Anum Shafique, Kashif Sultan, Faisal Shah, Najmul Hassan Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective |
title | Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective |
title_full | Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective |
title_fullStr | Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective |
title_full_unstemmed | Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective |
title_short | Hepatocellular Carcinoma in Pakistan: National Trends and Global Perspective |
title_sort | hepatocellular carcinoma in pakistan: national trends and global perspective |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756136/ https://www.ncbi.nlm.nih.gov/pubmed/26955390 http://dx.doi.org/10.1155/2016/5942306 |
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