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Angiotensin-converting enzyme 2/angiotensin-(1–7)/Mas axis activates Akt signaling to ameliorate hepatic steatosis

The classical axis of renin-angiotensin system (RAS), angiotensin (Ang)-converting enzyme (ACE)/Ang II/AT1, contributes to the development of non-alcoholic fatty liver disease (NAFLD). However, the role of bypass axis of RAS (Angiotensin-converting enzyme 2 (ACE2)/Ang-(1–7)/Mas) in hepatic steatosis...

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Detalles Bibliográficos
Autores principales: Cao, Xi, Yang, Fangyuan, Shi, Tingting, Yuan, Mingxia, Xin, Zhong, Xie, Rongrong, Li, Sen, Li, Hongbing, Yang, Jin-Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756304/
https://www.ncbi.nlm.nih.gov/pubmed/26883384
http://dx.doi.org/10.1038/srep21592