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Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese
Obesity is usually considered to predispose to atherosclerotic cardiovascular disease (ASCVD) but milder degrees of obesity or overweight may be protective in some elderly populations. We examined the relationships between general and abdominal obesity indices with ASCVD and its risk factors in elde...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756331/ https://www.ncbi.nlm.nih.gov/pubmed/26882876 http://dx.doi.org/10.1038/srep21521 |
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author | Fan, Huimin Li, Xiaolin Zheng, Liang Chen, Xiaoli lan, Qin Wu, Hong Ding, Xugang Qian, Dingguang Shen, Yixin Yu, Zuoren Fan, Lieying Chen, Ming Tomlinson, Brian Chan, Paul Zhang, Yuzhen Liu, Zhongmin |
author_facet | Fan, Huimin Li, Xiaolin Zheng, Liang Chen, Xiaoli lan, Qin Wu, Hong Ding, Xugang Qian, Dingguang Shen, Yixin Yu, Zuoren Fan, Lieying Chen, Ming Tomlinson, Brian Chan, Paul Zhang, Yuzhen Liu, Zhongmin |
author_sort | Fan, Huimin |
collection | PubMed |
description | Obesity is usually considered to predispose to atherosclerotic cardiovascular disease (ASCVD) but milder degrees of obesity or overweight may be protective in some elderly populations. We examined the relationships between general and abdominal obesity indices with ASCVD and its risk factors in elderly (aged ≥65 years) Shanghai community residents Among the 3950 participants, 21.5% had ASCVD, 56.2% had body mass index (BMI) ≥24 kg/m2, 50.1% had high waist circumference (WC) and 77.1% had waist-to-height ratio (WHtR) ≥0.50. WHtR increased with age in both men and women whereas WC increased with age only in women and BMI decreased with age only in men. The optimal WHtR cut-off value to predict the risk of ASCVD determined by receiver operating characteristic analysis was WHtR ≥0.53 with a prevalence of 55.8%. Having abdominal obesity was significantly associated with prevalent ASCVD with WHtR ≥0.53 having a higher value for the odds ratio than high WC, whereas high BMI was not associated. All three indices predicted high glucose, triglycerides and hsCRP levels but only the WHtR ≥0.53 showed a significant association with physical activity. Abdominal obesity indices, but not BMI, predicted prevalent ASCVD and its risk factors in this elderly Chinese population. |
format | Online Article Text |
id | pubmed-4756331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-47563312016-02-25 Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese Fan, Huimin Li, Xiaolin Zheng, Liang Chen, Xiaoli lan, Qin Wu, Hong Ding, Xugang Qian, Dingguang Shen, Yixin Yu, Zuoren Fan, Lieying Chen, Ming Tomlinson, Brian Chan, Paul Zhang, Yuzhen Liu, Zhongmin Sci Rep Article Obesity is usually considered to predispose to atherosclerotic cardiovascular disease (ASCVD) but milder degrees of obesity or overweight may be protective in some elderly populations. We examined the relationships between general and abdominal obesity indices with ASCVD and its risk factors in elderly (aged ≥65 years) Shanghai community residents Among the 3950 participants, 21.5% had ASCVD, 56.2% had body mass index (BMI) ≥24 kg/m2, 50.1% had high waist circumference (WC) and 77.1% had waist-to-height ratio (WHtR) ≥0.50. WHtR increased with age in both men and women whereas WC increased with age only in women and BMI decreased with age only in men. The optimal WHtR cut-off value to predict the risk of ASCVD determined by receiver operating characteristic analysis was WHtR ≥0.53 with a prevalence of 55.8%. Having abdominal obesity was significantly associated with prevalent ASCVD with WHtR ≥0.53 having a higher value for the odds ratio than high WC, whereas high BMI was not associated. All three indices predicted high glucose, triglycerides and hsCRP levels but only the WHtR ≥0.53 showed a significant association with physical activity. Abdominal obesity indices, but not BMI, predicted prevalent ASCVD and its risk factors in this elderly Chinese population. Nature Publishing Group 2016-02-17 /pmc/articles/PMC4756331/ /pubmed/26882876 http://dx.doi.org/10.1038/srep21521 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Fan, Huimin Li, Xiaolin Zheng, Liang Chen, Xiaoli lan, Qin Wu, Hong Ding, Xugang Qian, Dingguang Shen, Yixin Yu, Zuoren Fan, Lieying Chen, Ming Tomlinson, Brian Chan, Paul Zhang, Yuzhen Liu, Zhongmin Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese |
title | Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese |
title_full | Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese |
title_fullStr | Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese |
title_full_unstemmed | Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese |
title_short | Abdominal obesity is strongly associated with Cardiovascular Disease and its Risk Factors in Elderly and very Elderly Community-dwelling Chinese |
title_sort | abdominal obesity is strongly associated with cardiovascular disease and its risk factors in elderly and very elderly community-dwelling chinese |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756331/ https://www.ncbi.nlm.nih.gov/pubmed/26882876 http://dx.doi.org/10.1038/srep21521 |
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