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Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism
BACKGROUND: Thrombus formation, a phenomenon primarily related to increased platelet activation, plays a key role in cardiovascular and cerebrovascular diseases. Although the established antiplatelet agents, such as aspirin and clopidogrel, have been shown to be beneficial in treating thromboembolic...
Autores principales: | Yen, Ting-Lin, Wu, Ming-Ping, Chung, Chi-Li, Yang, Wen-Bin, Jayakumar, Thanasekaran, Geraldine, Pitchairaj, Chou, Chih-Ming, Chang, Chia-Yau, Lu, Wan-Jung, Sheu, Joen-Rong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756413/ https://www.ncbi.nlm.nih.gov/pubmed/26887315 http://dx.doi.org/10.1186/s12929-016-0245-4 |
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