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Novel synthetic benzimidazole-derived oligosaccharide, M3BIM, prevents ex vivo platelet aggregation and in vivo thromboembolism

BACKGROUND: Thrombus formation, a phenomenon primarily related to increased platelet activation, plays a key role in cardiovascular and cerebrovascular diseases. Although the established antiplatelet agents, such as aspirin and clopidogrel, have been shown to be beneficial in treating thromboembolic...

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Detalles Bibliográficos
Autores principales: Yen, Ting-Lin, Wu, Ming-Ping, Chung, Chi-Li, Yang, Wen-Bin, Jayakumar, Thanasekaran, Geraldine, Pitchairaj, Chou, Chih-Ming, Chang, Chia-Yau, Lu, Wan-Jung, Sheu, Joen-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756413/
https://www.ncbi.nlm.nih.gov/pubmed/26887315
http://dx.doi.org/10.1186/s12929-016-0245-4

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