Solamargine triggers cellular necrosis selectively in different types of human melanoma cancer cells through extrinsic lysosomal mitochondrial death pathway

BACKGROUND: Previous reports showed that the Steroidal Glycoalkaloid Solamargine inhibited proliferation of non-melanoma skin cancer cells. However, Solamargine was not tested systematically on different types of melanoma cells and was not simultaneously tested on normal cells either. In this study...

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Detalles Bibliográficos
Autores principales: Al Sinani, Sana S., Eltayeb, Elsadig A., Coomber, Brenda L., Adham, Sirin A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Primary Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756414/
https://www.ncbi.nlm.nih.gov/pubmed/26889092
http://dx.doi.org/10.1186/s12935-016-0287-4

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