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Do schistosome vaccine trials in mice have an intrinsic flaw that generates spurious protection data?
The laboratory mouse has been widely used to test the efficacy of schistosome vaccines and a long list of candidates has emerged from this work, many of them abundant internal proteins. These antigens do not have an additive effect when co-administered, or delivered as SWAP homogenate, a quarter of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756456/ https://www.ncbi.nlm.nih.gov/pubmed/26888413 http://dx.doi.org/10.1186/s13071-016-1369-9 |