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Activation of EGFR by small compounds through coupling the generation of hydrogen peroxide to stable dimerization of Cu/Zn SOD1

Activation of cell signaling by reactive chemicals and pollutants is an important issue for human health. It has been shown that lipophilic nitro-benzoxadiazole (NBD) compounds rapidly move across the plasma membrane and enhance Epidermal Growth Factor Receptor (EGFR) tyrosine phosphorylation in can...

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Detalles Bibliográficos
Autores principales:	Sakanyan, Vehary, Hulin, Philippe, Alves de Sousa, Rodolphe, Silva, Viviane A. O., Hambardzumyan, Artur, Nedellec, Steven, Tomasoni, Christophe, Logé, Cédric, Pineau, Charles, Roussakis, Christos, Fleury, Fabrice, Artaud, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756678/ https://www.ncbi.nlm.nih.gov/pubmed/26883293 http://dx.doi.org/10.1038/srep21088

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