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ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs
Key to realizing the diagnostic and therapeutic potential of human brown/brite adipocytes is the identification of a renewable, easily accessible and safe tissue source of progenitor cells, and an efficacious in vitro differentiation protocol. We show that macromolecular crowding (MMC) facilitates b...
Autores principales: | Lee, Michelle H., Goralczyk, Anna G., Kriszt, Rókus, Ang, Xiu Min, Badowski, Cedric, Li, Ying, Summers, Scott A., Toh, Sue-Anne, Yassin, M. Shabeer, Shabbir, Asim, Sheppard, Allan, Raghunath, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756694/ https://www.ncbi.nlm.nih.gov/pubmed/26883894 http://dx.doi.org/10.1038/srep21173 |
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