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Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice

BACKGROUND: Ketamine produces schizophrenia-like behavioral phenotypes in healthy people. Prolonged ketamine effects and exacerbation of symptoms after the administration of ketamine have been observed in patients with schizophrenia. More recently, ketamine has been used as a potent antidepressant t...

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Detalles Bibliográficos
Autores principales:	Higa, Kerin K., Ji, Baohu, Buell, Mahalah R., Risbrough, Victoria B., Powell, Susan B., Young, Jared W., Geyer, Mark A., Zhou, Xianjin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756721/ https://www.ncbi.nlm.nih.gov/pubmed/26037489 http://dx.doi.org/10.1093/ijnp/pyv063

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