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Structural transitions during prothrombin activation: On the importance of fragment 2
Prothrombin is activated to thrombin by the prothrombinase complex through sequential cleavage at two distinct sites. This occurs at sites of vascular injury in a highly regulated cascade of serine protease and cofactor activation, where activated platelets provide a suitable surface for protease/co...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Editions Scientifiques Elsevier
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756804/ https://www.ncbi.nlm.nih.gov/pubmed/26365066 http://dx.doi.org/10.1016/j.biochi.2015.09.013 |