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The expression of a viral microRNA is regulated by clustering to allow optimal B cell transformation

The Epstein-Barr virus (EBV) transforms B cells by expressing latent proteins and the BHRF1 microRNA cluster. MiR-BHRF1–3, its most transforming member, belongs to the recently identified group of weakly expressed microRNAs. We show here that miR-BHRF1–3 displays an unusually low propensity to form...

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Detalles Bibliográficos
Autores principales:	Haar, Janina, Contrant, Maud, Bernhardt, Katharina, Feederle, Regina, Diederichs, Sven, Pfeffer, Sébastien, Delecluse, Henri-Jacques
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756819/ https://www.ncbi.nlm.nih.gov/pubmed/26635399 http://dx.doi.org/10.1093/nar/gkv1330

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