Binding of transcription factor GabR to DNA requires recognition of DNA shape at a location distinct from its cognate binding site

Mechanisms for transcription factor recognition of specific DNA base sequences are well characterized and recent studies demonstrate that the shape of these cognate binding sites is also important. Here, we uncover a new mechanism where the transcription factor GabR simultaneously recognizes two cog...

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Detalles Bibliográficos
Autores principales: Al-Zyoud, Walid A., Hynson, Robert MG., Ganuelas, Lorraine A., Coster, Adelle CF., Duff, Anthony P., Baker, Matthew AB., Stewart, Alastair G., Giannoulatou, Eleni, Ho, Joshua WK., Gaus, Katharina, Liu, Dali, Lee, Lawrence K., Böcking, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756830/
https://www.ncbi.nlm.nih.gov/pubmed/26681693
http://dx.doi.org/10.1093/nar/gkv1466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756830/
https://www.ncbi.nlm.nih.gov/pubmed/26681693
http://dx.doi.org/10.1093/nar/gkv1466

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