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Analysis of LexA binding sites and transcriptomics in response to genotoxic stress in Leptospira interrogans

We determined the effects of DNA damage caused by ultraviolet radiation on gene expression in Leptospira interrogans using DNA microarrays. These data were integrated with DNA binding in vivo of LexA1, a regulator of the DNA damage response, assessed by chromatin immunoprecipitation and massively pa...

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Detalles Bibliográficos
Autores principales: Schons-Fonseca, Luciane, da Silva, Josefa B., Milanez, Juliana S., Domingos, Renan H., Smith, Janet L., Nakaya, Helder I., Grossman, Alan D., Ho, Paulo L., da Costa, Renata MA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756842/
https://www.ncbi.nlm.nih.gov/pubmed/26762976
http://dx.doi.org/10.1093/nar/gkv1536

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