Alternative splicing creates two new architectures for human tyrosyl-tRNA synthetase

Many human tRNA synthetases evolved alternative functions outside of protein synthesis. These functions are associated with over 200 splice variants (SVs), most of which are catalytic nulls that engender new biology. While known to regulate non-translational activities, little is known about structu...

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Detalles Bibliográficos
Autores principales: Wei, Zhiyi, Xu, Zhiwen, Liu, Xiaotian, Lo, Wing-Sze, Ye, Fei, Lau, Ching-Fun, Wang, Feng, Zhou, Jie J., Nangle, Leslie A., Yang, Xiang-Lei, Zhang, Mingjie, Schimmel, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756856/
https://www.ncbi.nlm.nih.gov/pubmed/26773056
http://dx.doi.org/10.1093/nar/gkw002

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