Caffeine Suppresses Apoptosis of Bladder Cancer RT4 Cells in Response to Ionizing Radiation by Inhibiting Ataxia Telangiectasia Mutated-Chk2-p53 Axis

BACKGROUND: Caffeine suppresses ataxia telangiectasia and Rad3 related and ataxia telangiectasia mutated (ATM) activities; ATM is the major kinase for DNA damage detection. This study aimed to investigate the effects of caffeine on DNA damage responses in cells from the bladder cancer cell line RT4...

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Detalles Bibliográficos
Autores principales: Zhang, Zhe-Wei, Xiao, Jing, Luo, Wei, Wang, Bo-Han, Chen, Ji-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756903/
https://www.ncbi.nlm.nih.gov/pubmed/26521794
http://dx.doi.org/10.4103/0366-6999.168065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4756903/
https://www.ncbi.nlm.nih.gov/pubmed/26521794
http://dx.doi.org/10.4103/0366-6999.168065

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