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Robotic Salvage Lymph Node Dissection After Radical Prostatectomy

INTRODUCTION AND OBJECTIVE: Radical prostatectomy is a first-line treatment for localized prostate cancer. However, in some cases, biochemical recurrence associated with imaging-detected nodal metastases may happen. Herein, we aim to present the surgical technique for salvage lymph node dissection a...

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Autores principales: Torricelli, Fabio C. M., Cividanes, Arnaldo, Guglielmetti, Giuliano B., Coelho, Rafael F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Urologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757015/
https://www.ncbi.nlm.nih.gov/pubmed/26401879
http://dx.doi.org/10.1590/S1677-5538.IBJU.2014.0614
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author Torricelli, Fabio C. M.
Cividanes, Arnaldo
Guglielmetti, Giuliano B.
Coelho, Rafael F.
author_facet Torricelli, Fabio C. M.
Cividanes, Arnaldo
Guglielmetti, Giuliano B.
Coelho, Rafael F.
author_sort Torricelli, Fabio C. M.
collection PubMed
description INTRODUCTION AND OBJECTIVE: Radical prostatectomy is a first-line treatment for localized prostate cancer. However, in some cases, biochemical recurrence associated with imaging-detected nodal metastases may happen. Herein, we aim to present the surgical technique for salvage lymph node dissection after radical prostatectomy. MATERIALS AND METHODS: A 70 year-old asymptomatic man presented with a prostate-specific antigen (PSA) of 7.45ng/ mL. Digital rectal examination was normal and trans-rectal prostate biopsy revealed a prostate adenocarcinoma Gleason 7 (3+4). Pre-operative computed tomography scan and bone scintigraphy showed no metastatic disease. In other service, the patient underwent a robotic-assisted radical prostatectomy plus obturador lymphadenectomy. Pathologic examination showed a pT3aN0 tumor. After 6 months of follow-up, serum PSA was 1.45ng/mL. Further investigation with 11C–Choline PET/CT revealed only a 2-cm lymph node close to the left internal iliac artery. The patient was counseled for salvage lymph node dissection. RESULTS: Salvage lymph node dissection was uneventfully performed. Operative time was 1.5 hour, blood loss was minimal, and there were no intra- or postoperative complications. The patient was discharged from hospital in the 1st postoperative day. After 12 months of follow-up, his PSA was undetectable with no other adjuvant therapy. CONCLUSION: Robotic salvage pelvic lymph node dissection is an effective option for treatment of patients with biochemical recurrence after radical prostatectomy and only pelvic lymph node metastasis detected by C11-Choline PET/CT.
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spelling pubmed-47570152016-05-09 Robotic Salvage Lymph Node Dissection After Radical Prostatectomy Torricelli, Fabio C. M. Cividanes, Arnaldo Guglielmetti, Giuliano B. Coelho, Rafael F. Int Braz J Urol Video Section INTRODUCTION AND OBJECTIVE: Radical prostatectomy is a first-line treatment for localized prostate cancer. However, in some cases, biochemical recurrence associated with imaging-detected nodal metastases may happen. Herein, we aim to present the surgical technique for salvage lymph node dissection after radical prostatectomy. MATERIALS AND METHODS: A 70 year-old asymptomatic man presented with a prostate-specific antigen (PSA) of 7.45ng/ mL. Digital rectal examination was normal and trans-rectal prostate biopsy revealed a prostate adenocarcinoma Gleason 7 (3+4). Pre-operative computed tomography scan and bone scintigraphy showed no metastatic disease. In other service, the patient underwent a robotic-assisted radical prostatectomy plus obturador lymphadenectomy. Pathologic examination showed a pT3aN0 tumor. After 6 months of follow-up, serum PSA was 1.45ng/mL. Further investigation with 11C–Choline PET/CT revealed only a 2-cm lymph node close to the left internal iliac artery. The patient was counseled for salvage lymph node dissection. RESULTS: Salvage lymph node dissection was uneventfully performed. Operative time was 1.5 hour, blood loss was minimal, and there were no intra- or postoperative complications. The patient was discharged from hospital in the 1st postoperative day. After 12 months of follow-up, his PSA was undetectable with no other adjuvant therapy. CONCLUSION: Robotic salvage pelvic lymph node dissection is an effective option for treatment of patients with biochemical recurrence after radical prostatectomy and only pelvic lymph node metastasis detected by C11-Choline PET/CT. Sociedade Brasileira de Urologia 2015 /pmc/articles/PMC4757015/ /pubmed/26401879 http://dx.doi.org/10.1590/S1677-5538.IBJU.2014.0614 Text en http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Video Section
Torricelli, Fabio C. M.
Cividanes, Arnaldo
Guglielmetti, Giuliano B.
Coelho, Rafael F.
Robotic Salvage Lymph Node Dissection After Radical Prostatectomy
title Robotic Salvage Lymph Node Dissection After Radical Prostatectomy
title_full Robotic Salvage Lymph Node Dissection After Radical Prostatectomy
title_fullStr Robotic Salvage Lymph Node Dissection After Radical Prostatectomy
title_full_unstemmed Robotic Salvage Lymph Node Dissection After Radical Prostatectomy
title_short Robotic Salvage Lymph Node Dissection After Radical Prostatectomy
title_sort robotic salvage lymph node dissection after radical prostatectomy
topic Video Section
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757015/
https://www.ncbi.nlm.nih.gov/pubmed/26401879
http://dx.doi.org/10.1590/S1677-5538.IBJU.2014.0614
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