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Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach

BACKGROUND: Tetralogy of Fallot (TOF) is a well-recognized congenital heart disease. Despite improvements in the outcomes of surgical repair, the optimal timing of surgery and type of surgical management of patients with TOF remains controversial. The purpose of this study was to assess outcomes fol...

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Autores principales: Bigdelian, Hamid, Sedighi, Mohsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society for Thoracic and Cardiovascular Surgery 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757391/
https://www.ncbi.nlm.nih.gov/pubmed/26889440
http://dx.doi.org/10.5090/kjtcs.2016.49.1.9
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author Bigdelian, Hamid
Sedighi, Mohsen
author_facet Bigdelian, Hamid
Sedighi, Mohsen
author_sort Bigdelian, Hamid
collection PubMed
description BACKGROUND: Tetralogy of Fallot (TOF) is a well-recognized congenital heart disease. Despite improvements in the outcomes of surgical repair, the optimal timing of surgery and type of surgical management of patients with TOF remains controversial. The purpose of this study was to assess outcomes following the repair of TOF in infants depending on the surgical procedure used. METHODS: This study involved the retrospective review of 120 patients who underwent TOF repair between 2010 and 2013. Patients were divided into three groups depending on the surgical procedure that they underwent. Corrective surgery was done via the transventricular approach (n=40), the transatrial approach (n=40), or a combined atrioventricular approach (n=40). Demographic data and the outcomes of the surgical procedures were compared among the groups. RESULTS: In the atrioventricular group, the incidence of the following complications was found to be significantly lower than in the other groups: complete heart block (p=0.034), right ventricular failure (p=0.027) and mediastinal bleeding (p=0.007). Patients in the atrioventricular group had a better postoperative right ventricular ejection fraction (p=0.001). No statistically significant differences were observed among the three surgical groups in the occurrence of tachycardia, renal failure, and tricuspid incompetence. The one-year survival rates in the three groups were 95%, 90%, and 97.5%, respectively (p=0.395). CONCLUSION: Combined atrioventricular repair of TOF in infancy can be safely performed, with acceptable surgical risk, a low incidence of reoperation, good ventricular function outcomes, and an excellent survival rate.
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spelling pubmed-47573912016-02-17 Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach Bigdelian, Hamid Sedighi, Mohsen Korean J Thorac Cardiovasc Surg Clinical Research BACKGROUND: Tetralogy of Fallot (TOF) is a well-recognized congenital heart disease. Despite improvements in the outcomes of surgical repair, the optimal timing of surgery and type of surgical management of patients with TOF remains controversial. The purpose of this study was to assess outcomes following the repair of TOF in infants depending on the surgical procedure used. METHODS: This study involved the retrospective review of 120 patients who underwent TOF repair between 2010 and 2013. Patients were divided into three groups depending on the surgical procedure that they underwent. Corrective surgery was done via the transventricular approach (n=40), the transatrial approach (n=40), or a combined atrioventricular approach (n=40). Demographic data and the outcomes of the surgical procedures were compared among the groups. RESULTS: In the atrioventricular group, the incidence of the following complications was found to be significantly lower than in the other groups: complete heart block (p=0.034), right ventricular failure (p=0.027) and mediastinal bleeding (p=0.007). Patients in the atrioventricular group had a better postoperative right ventricular ejection fraction (p=0.001). No statistically significant differences were observed among the three surgical groups in the occurrence of tachycardia, renal failure, and tricuspid incompetence. The one-year survival rates in the three groups were 95%, 90%, and 97.5%, respectively (p=0.395). CONCLUSION: Combined atrioventricular repair of TOF in infancy can be safely performed, with acceptable surgical risk, a low incidence of reoperation, good ventricular function outcomes, and an excellent survival rate. The Korean Society for Thoracic and Cardiovascular Surgery 2016-02 2016-02-05 /pmc/articles/PMC4757391/ /pubmed/26889440 http://dx.doi.org/10.5090/kjtcs.2016.49.1.9 Text en Copyright © 2016 by The Korean Society for Thoracic and Cardiovascular Surgery. All rights Reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Clinical Research
Bigdelian, Hamid
Sedighi, Mohsen
Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach
title Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach
title_full Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach
title_fullStr Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach
title_full_unstemmed Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach
title_short Repair of Tetralogy of Fallot in Infancy via the Atrioventricular Approach
title_sort repair of tetralogy of fallot in infancy via the atrioventricular approach
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757391/
https://www.ncbi.nlm.nih.gov/pubmed/26889440
http://dx.doi.org/10.5090/kjtcs.2016.49.1.9
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