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Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival

The histone demethylase JMJD1A, which controls gene expression by epigenetic regulation of H3K9 methylation marks, functions in diverse activities, including spermatogenesis, metabolism, and stem cell self-renewal and differentiation. Here, we found that JMJD1A knockdown in prostate cancer cells ant...

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Detalles Bibliográficos
Autores principales: Fan, Lingling, Peng, Guihong, Sahgal, Natasha, Fazli, Ladan, Gleave, Martin, Zhang, Yuji, Hussain, Arif, Qi, Jianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757517/
https://www.ncbi.nlm.nih.gov/pubmed/26279298
http://dx.doi.org/10.1038/onc.2015.309