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Embryonic Stem Cell (ES)-Specific Enhancers Specify the Expression Potential of ES Genes in Cancer

Cancers often display gene expression profiles resembling those of undifferentiated cells. The mechanisms controlling these expression programs have yet to be identified. Exploring transcriptional enhancers throughout hematopoietic cell development and derived cancers, we uncovered a novel class of...

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Detalles Bibliográficos
Autores principales: Aran, Dvir, Abu-Remaileh, Monther, Levy, Revital, Meron, Nurit, Toperoff, Gidon, Edrei, Yifat, Bergman, Yehudit, Hellman, Asaf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757527/
https://www.ncbi.nlm.nih.gov/pubmed/26886256
http://dx.doi.org/10.1371/journal.pgen.1005840

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