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Tetra-O-Methyl Nordihydroguaiaretic Acid Broadly Suppresses Cancer Metabolism and Synergistically Induces Strong Anticancer Activity in Combination with Etoposide, Rapamycin and UCN-01
The ability of Tetra-O-methyl nordihydroguaiaretic acid (M(4)N) to induce rapid cell death in combination with Etoposide, Rapamycin, or UCN-01 was examined in LNCaP cells, both in cell culture and animal experiments. Mice treated with M(4)N drug combinations with either Etoposide or Rapamycin showed...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757551/ https://www.ncbi.nlm.nih.gov/pubmed/26886430 http://dx.doi.org/10.1371/journal.pone.0148685 |