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Contrasting Inducible Knockdown of the Auxiliary PTEX Component PTEX88 in P. falciparum and P. berghei Unmasks a Role in Parasite Virulence
Pathogenesis of malaria infections is linked to remodeling of erythrocytes, a process dependent on the trafficking of hundreds of parasite-derived proteins into the host erythrocyte. Recent studies have demonstrated that the Plasmodium translocon of exported proteins (PTEX) serves as the central gat...
Autores principales: | Chisholm, Scott A., McHugh, Emma, Lundie, Rachel, Dixon, Matthew W. A., Ghosh, Sreejoyee, O’Keefe, Meredith, Tilley, Leann, Kalanon, Ming, de Koning-Ward, Tania F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757573/ https://www.ncbi.nlm.nih.gov/pubmed/26886275 http://dx.doi.org/10.1371/journal.pone.0149296 |
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