Blimp-1 controls plasma cell function through regulation of immunoglobulin secretion and the unfolded protein response

Plasma cell differentiation requires silencing of B cell transcription, while establishing antibody-secretory function and long-term survival. The transcription factors Blimp-1 and IRF4 are essential for plasma cell generation, however their function in mature plasma cells has remained elusive. We h...

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Detalles Bibliográficos
Autores principales: Tellier, Julie, Shi, Wei, Minnich, Martina, Liao, Yang, Crawford, Simon, Smyth, Gordon K, Kallies, Axel, Busslinger, Meinrad, Nutt, Stephen L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757736/
https://www.ncbi.nlm.nih.gov/pubmed/26779600
http://dx.doi.org/10.1038/ni.3348

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