Ablation of Type-1 IFN Signaling in Hematopoietic Cells Confers Protection Following Traumatic Brain Injury123

Type-1 interferons (IFNs) are pleiotropic cytokines that signal through the type-1 IFN receptor (IFNAR1). Recent literature has implicated the type-1 IFNs in disorders of the CNS. In this study, we have investigated the role of type-1 IFNs in neuroinflammation following traumatic brain injury (TBI)....

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Detalles Bibliográficos
Autores principales: Karve, Ila P., Zhang, Moses, Habgood, Mark, Frugier, Tony, Brody, Kate M., Sashindranath, Maithili, Ek, C. Joakim, Chappaz, Stephane, Kile, Ben T., Wright, David, Wang, Hong, Johnston, Leigh, Daglas, Maria, Ates, Robert C., Medcalf, Robert L., Taylor, Juliet M., Crack, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2016
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4757777/
https://www.ncbi.nlm.nih.gov/pubmed/27022620
http://dx.doi.org/10.1523/ENEURO.0128-15.2016

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