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Dnd knockout ablates germ cells and demonstrates germ cell independent sex differentiation in Atlantic salmon

Introgression of farmed salmon escapees into wild stocks is a major threat to the genetic integrity of wild populations. Using germ cell-free fish in aquaculture may mitigate this problem. Our study investigated whether it is possible to produce germ cell-free salmon in F0 by using CRISPR-Cas9 to kn...

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Detalles Bibliográficos
Autores principales:	Wargelius, Anna, Leininger, Sven, Skaftnesmo, Kai Ove, Kleppe, Lene, Andersson, Eva, Taranger, Geir Lasse, Schulz, Rüdiger W, Edvardsen, Rolf B
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758030/ https://www.ncbi.nlm.nih.gov/pubmed/26888627 http://dx.doi.org/10.1038/srep21284

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