Alcoholic hepatitis accelerates early hepatobiliary cancer by increasing stemness and miR-122-mediated HIF-1α activation

Alcohol-related hepatocellular carcinoma (HCC) develops with advanced alcoholic liver disease and liver fibrosis. Using adult mice, we evaluate the effect of alcoholic steatohepatitis on early hepatobiliary carcinoma after initiation by diethyl-nitrosamine (DEN). Here we show that alcohol-fed DEN-in...

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Detalles Bibliográficos
Autores principales: Ambade, Aditya, Satishchandran, Abhishek, Szabo, Gyongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758032/
https://www.ncbi.nlm.nih.gov/pubmed/26888602
http://dx.doi.org/10.1038/srep21340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758032/
https://www.ncbi.nlm.nih.gov/pubmed/26888602
http://dx.doi.org/10.1038/srep21340

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