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GeneiASE: Detection of condition-dependent and static allele-specific expression from RNA-seq data without haplotype information
Allele-specific expression (ASE) is the imbalance in transcription between maternal and paternal alleles at a locus and can be probed in single individuals using massively parallel DNA sequencing technology. Assessing ASE within a single sample provides a static picture of the ASE, but the magnitude...
Autores principales: | Edsgärd, Daniel, Iglesias, Maria Jesus, Reilly, Sarah-Jayne, Hamsten, Anders, Tornvall, Per, Odeberg, Jacob, Emanuelsson, Olof |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758070/ https://www.ncbi.nlm.nih.gov/pubmed/26887787 http://dx.doi.org/10.1038/srep21134 |
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