Binding interface change and cryptic variation in the evolution of protein-protein interactions

BACKGROUND: Physical interactions between proteins are essential for almost all biological functions and systems. To understand the evolution of function it is therefore important to understand the evolution of molecular interactions. Of key importance is the evolution of binding specificity, the se...

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Detalles Bibliográficos
Autores principales: Ames, Ryan M., Talavera, David, Williams, Simon G., Robertson, David L., Lovell, Simon C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758157/
https://www.ncbi.nlm.nih.gov/pubmed/26892785
http://dx.doi.org/10.1186/s12862-016-0608-1

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