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NanoLuc Luciferase – A Multifunctional Tool for High Throughput Antibody Screening

Based on the recent development of NanoLuc luciferase (Nluc), a small (19 kDa), highly stable, ATP independent, bioluminescent protein, an extremely robust and ultra high sensitivity screening system has been developed whereby primary hits of therapeutic antibodies and antibody fragments could be ch...

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Detalles Bibliográficos
Autores principales: Boute, Nicolas, Lowe, Peter, Berger, Sven, Malissard, Martine, Robert, Alain, Tesar, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758271/
https://www.ncbi.nlm.nih.gov/pubmed/26924984
http://dx.doi.org/10.3389/fphar.2016.00027