Cargando…

Inhibition of integrin β1 decreases the malignancy of ovarian cancer cells and potentiates anticancer therapy via the FAK/STAT1 signaling pathway

Integrin β1 (ITGB1) is frequently upregulated in ovarian cancer, and promotes ovarian tumorigenesis and cancer progression. However, the effects of ITGB1 inhibition on ovarian cancer progression and anticancer therapy remain to be elucidated. The results of the present study indicated that ITGB1 was...

Descripción completa

Detalles Bibliográficos
Autores principales:	ZHANG, LEI, ZOU, WEN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758278/ https://www.ncbi.nlm.nih.gov/pubmed/26497667 http://dx.doi.org/10.3892/mmr.2015.4443

Ejemplares similares

SPP1 promotes ovarian cancer progression via Integrin β1/FAK/AKT signaling pathway
por: Zeng, Biao, et al.
Publicado: (2018)

Inhibition of the integrin/FAK signaling axis and c-Myc synergistically disrupts ovarian cancer malignancy
por: Xu, B, et al.
Publicado: (2017)

αν and β1 Integrins Mediate Aβ-Induced Neurotoxicity in Hippocampal Neurons via the FAK Signaling Pathway
por: Han, Hai-Yan, et al.
Publicado: (2013)

Glucose Transporter 1 Promotes the Malignant Phenotype of Non-Small Cell Lung Cancer through Integrin β1/Src/FAK Signaling
por: Zhao, Huanyu, et al.
Publicado: (2019)

β1 integrin-mediated multicellular resistance in hepatocellular carcinoma through activation of the FAK/Akt pathway
por: Tian, Tao, et al.
Publicado: (2018)

An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer
por: Tai, Yu-Ling, et al.
Publicado: (2015)

Hydrogen Sulfide Recruits Macrophage Migration by Integrin β1-Src-FAK/Pyk2-Rac Pathway in Myocardial Infarction
por: Miao, Lei, et al.
Publicado: (2016)

Albumin fibrillization induces apoptosis via integrin/FAK/Akt pathway
por: Huang, Chun-Yung, et al.
Publicado: (2009)

Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2016)

Collagen triple helix repeat containing 1 (CTHRC1) activates Integrin β3/FAK signaling and promotes metastasis in ovarian cancer
por: Guo, Biying, et al.
Publicado: (2017)

Inhibition of Integrin α(v)β(3)-FAK-MAPK signaling constrains the invasion of T-ALL cells
por: Huang, Lan, et al.
Publicado: (2023)

Activated networking of platelet activating factor receptor and FAK/STAT1 induces malignant potential in BRCA1-mutant at-risk ovarian epithelium
por: Zhang, Lifang, et al.
Publicado: (2010)

Integrin β1/FAK/SRC signal pathway is involved in autism spectrum disorder in Tspan7 knockout rats
por: Pang, Shuo, et al.
Publicado: (2022)

Bufalin enhances antitumor effect of paclitaxel on cervical tumorigenesis via inhibiting the integrin α2/β5/FAK signaling pathway
por: Liu, Fei, et al.
Publicado: (2016)

Phosphatase regenerating liver 3 participates in Integrinβ1/FAK-Src/MAPK signaling pathway and contributes to the regulation of malignant behaviors in hepatocellular carcinoma cells
por: Chen, Guobin, et al.
Publicado: (2023)

Functionalized self-assembling peptide improves INS-1 β-cell function and proliferation via the integrin/FAK/ERK/cyclin pathway
por: Liu, Jingping, et al.
Publicado: (2015)

Down-Regulation of Gli Transcription Factor Leads to the Inhibition of Migration and Invasion of Ovarian Cancer Cells via Integrin β4-Mediated FAK Signaling
por: Chen, Qi, et al.
Publicado: (2014)

Effects of Kindlin-2 on proliferation and migration of VSMC and integrinβ1 andβ3 activity via FAK-PI3K signaling pathway
por: Wu, Xiaolin, et al.
Publicado: (2020)

MYO10 contributes to the malignant phenotypes of colorectal cancer via RACK1 by activating integrin/Src/FAK signaling
por: Ou, Haibin, et al.
Publicado: (2022)

NPTX1 promotes metastasis via integrin/FAK signaling in gastric cancer
por: Yan, Hongfei, et al.
Publicado: (2019)

Erratum to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2017)

Correction to: Integrin-FAK signaling rapidly and potently promotes mitochondrial function through STAT3
por: Visavadiya, Nishant P., et al.
Publicado: (2020)

FOXO1 inhibits FSL-1 regulation of integrin β6 by blocking STAT3 binding to the integrin β6 gene promoter
por: Xu, Mingyan, et al.
Publicado: (2022)

Author Correction: Hydrogen Sulfide Recruits Macrophage Migration by Integrin β1-Src-FAK/Pyk2-Rac Pathway in Myocardial Infarction
por: Miao, Lei, et al.
Publicado: (2022)

Vasodilator-stimulated phosphoprotein promotes liver metastasis of gastrointestinal cancer by activating a β1-integrin-FAK-YAP1/TAZ signaling pathway
por: Xiang, Xiaoyu, et al.
Publicado: (2018)

Intravital Imaging Reveals How BRAF Inhibition Generates Drug-Tolerant Microenvironments with High Integrin β1/FAK Signaling
por: Hirata, Eishu, et al.
Publicado: (2015)

Conformation-dependent binding of a Tetrastatin peptide to α(v)β(3) integrin decreases melanoma progression through FAK/PI(3)K/Akt pathway inhibition
por: Lambert, Eléonore, et al.
Publicado: (2018)

αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium
por: Roggia, Murilo F., et al.
Publicado: (2015)

EGCG Promotes Neurite Outgrowth through the Integrin β1/FAK/p38 Signaling Pathway after Subarachnoid Hemorrhage
por: Zhang, Yuyuan, et al.
Publicado: (2021)

MFAP2 is overexpressed in gastric cancer and promotes motility via the MFAP2/integrin α5β1/FAK/ERK pathway
por: Yao, Li-wen, et al.
Publicado: (2020)

Overexpression of HAb18G/CD147 promotes invasion and metastasis via α3β1 integrin mediated FAK-paxillin and FAK-PI3K-Ca(2+) pathways
por: Tang, J., et al.
Publicado: (2008)

Role of Site-Specific Glycosylation in the I-Like Domain of Integrin β1 in Small Extracellular Vesicle-Mediated Malignant Behavior and FAK Activation
por: Cao, Lin, et al.
Publicado: (2021)

Fluid shear stress and endothelial cells synergistically promote osteogenesis of mesenchymal stem cells via integrin β1-FAK-ERK1/2 pathway
por: JIANG, Mingli, et al.
Publicado: (2021)

Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis
por: Huang, Chi-Ruei, et al.
Publicado: (2015)

Stretch of β1 Integrin Activates an Outwardly Rectifying Chloride Current via FAK and Src in Rabbit Ventricular Myocytes
por: Browe, David M., et al.
Publicado: (2003)

EZH2 engages TGFβ signaling to promote breast cancer bone metastasis via integrin β1-FAK activation
por: Zhang, Lin, et al.
Publicado: (2022)

NPTX1 Promotes Metastasis via Integrin/FAK Signaling in Gastric Cancer [Retraction]
Publicado: (2023)

Collagen I promotes hepatocellular carcinoma cell proliferation by regulating integrin β1/FAK signaling pathway in nonalcoholic fatty liver
por: Zheng, Xinglong, et al.
Publicado: (2017)

Integrin-mediated Activation of MAP Kinase Is Independent of FAK: Evidence for Dual Integrin Signaling Pathways in Fibroblasts
por: Lin, Tsung H., et al.
Publicado: (1997)

Crabp2 Promotes Metastasis of Lung Cancer Cells via HuR and Integrin β1/FAK/ERK Signaling
por: Wu, Jun-I, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_948opevtalf2r69r4bra5mo8vp