Novel hydroxybutyl chitosan nanoparticles for siRNA delivery targeting tissue factor inhibits proliferation and induces apoptosis in human vascular smooth muscle cells

Chitosan, a polysaccharide isolated from shrimp and other crustacean shells, has been widely investigated for DNA and siRNA delivery. Despite substantial effort having been made to improve chitosan as a non-viral gene delivery vector, the application is severely limited by its poor solubility under...

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Detalles Bibliográficos
Autores principales: WAN, KANG, LI, JIAN, LI, DAN, GE, JUNHUA, WANG, YUNLONG, LI, XUEXUN, GUO, YONGFANG, GUO, JUNJIE, LENG, MIN, WANG, PAN, AN, YI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758285/
https://www.ncbi.nlm.nih.gov/pubmed/26497351
http://dx.doi.org/10.3892/mmr.2015.4461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758285/
https://www.ncbi.nlm.nih.gov/pubmed/26497351
http://dx.doi.org/10.3892/mmr.2015.4461

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