Cargando…

Suppression of A549 cell proliferation and metastasis by calycosin via inhibition of the PKC-α/ERK1/2 pathway: An in vitro investigation

Mostrar otras versiones (1)

The migration and invasion of lung cancer cells into the extracellular matrix contributes to the high mortality rates of lung cancer. The protein kinase C (PKC) and downstream signaling pathways are important in the invasion and migration of lung cancer cells. Calycosin (Cal), an effector chemical f...

Descripción completa

Detalles Bibliográficos
Autores principales:	CHENG, XU-DONG, GU, JUN-FEI, YUAN, JIA-RUI, FENG, LIANG, JIA, XIAO-BIN
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758323/ https://www.ncbi.nlm.nih.gov/pubmed/26498639 http://dx.doi.org/10.3892/mmr.2015.4449

Ejemplares similares

Suppression of A549 cell proliferation and metastasis by calycosin via inhibition of the PKC-α/ERK1/2 pathway: An in vitro investigation
por: CHENG, XU-DONG, et al.
Publicado: (2016)

Differential phosphorylation of NG2 proteoglycan by ERK and PKCα helps balance cell proliferation and migration
por: Makagiansar, Irwan T., et al.
Publicado: (2007)

Pharmacological targets and mechanisms of calycosin against meningitis
por: Nong, Yuan, et al.
Publicado: (2020)

Thrombin induces epithelial-mesenchymal transition via PAR-1, PKC, and ERK1/2 pathways in A549 cells
por: Song, Jeong Sup, et al.
Publicado: (2013)

Investigation of Effects and Mechanisms of Total Flavonoids of Astragalus and Calycosin on Human Erythroleukemia Cells
por: Zhang, Dongqing, et al.
Publicado: (2012)

Calycosin alleviates allergic contact dermatitis by repairing epithelial tight junctions via down‐regulating HIF‐1α
por: Jia, Zhirong, et al.
Publicado: (2018)

Calycosin Suppresses RANKL-Mediated Osteoclastogenesis through Inhibition of MAPKs and NF-κB
por: Quan, Gui-Hua, et al.
Publicado: (2015)

Calycosin Ameliorates Bleomycin-Induced Pulmonary Fibrosis via Suppressing Oxidative Stress, Apoptosis, and Enhancing Autophagy
por: Liu, Haoge, et al.
Publicado: (2022)

Calycosin Ameliorates Diabetes-Induced Renal Inflammation via the NF-κB Pathway In Vitro and In Vivo
por: Zhang, Ying-ying, et al.
Publicado: (2019)

Calycosin inhibits hepatocyte apoptosis in acute liver failure by suppressing the TLR4/NF‐κB pathway: An in vitro study
por: Chang, Le, et al.
Publicado: (2023)

ER-α36, a Novel Variant of ER-α, Mediates Estrogen-Stimulated Proliferation of Endometrial Carcinoma Cells via the PKCδ/ERK Pathway
por: Tong, Jing-Shan, et al.
Publicado: (2010)

PKCα and PKCδ: Friends and Rivals
por: Black, Jennifer D., et al.
Publicado: (2022)

MicroRNA-150 suppresses cell proliferation and metastasis in hepatocellular carcinoma by inhibiting the GAB1-ERK axis
por: Sun, Wei, et al.
Publicado: (2016)

A novel antiproliferative PKCα-Ras-ERK signaling axis in intestinal epithelial cells
por: Kaur, Navneet, et al.
Publicado: (2022)

A Ferulic Acid Derivative FXS-3 Inhibits Proliferation and Metastasis of Human Lung Cancer A549 Cells via Positive JNK Signaling Pathway and Negative ERK/p38, AKT/mTOR and MEK/ERK Signaling Pathways
por: Yue, Shi-Jun, et al.
Publicado: (2019)

ADAMTS8 targets ERK to suppress cell proliferation, invasion, and metastasis of hepatocellular carcinoma
por: Zhao, Xuetao, et al.
Publicado: (2018)

Metformin Inhibits Tumor Metastasis through Suppressing Hsp90α Secretion in an AMPKα1-PKCγ Dependent Manner
por: Gong, Yuanchao, et al.
Publicado: (2020)

Calycosin Influences the Metabolism of Five Probe Drugs in Rats
por: Wu, Mei-ling, et al.
Publicado: (2020)

Calycosin prevents bone loss induced by hindlimb unloading
por: Jin, Xiang, et al.
Publicado: (2022)

The Role of TRPC6 in the Neuroprotection of Calycosin Against Cerebral Ischemic Injury
por: Guo, Chao, et al.
Publicado: (2017)

PPP1R14D promotes the proliferation, migration and invasion of lung adenocarcinoma via the PKCα/BRAF/MEK/ERK signaling pathway
por: Cao, Huijun, et al.
Publicado: (2022)

12-Deoxyphorbol Esters Induce Growth Arrest and Apoptosis in Human Lung Cancer A549 Cells Via Activation of PKC-δ/PKD/ERK Signaling Pathway
por: Tsai, Ju-Ying, et al.
Publicado: (2020)

Effects of 2,2′,4′-trihydroxychalcone on the proliferation, metastasis and apoptosis of A549 human lung cancer cells
por: Sun, Jia-Lin, et al.
Publicado: (2022)

Therapeutic targets and molecular mechanism of calycosin for the treatment of cerebral ischemia/reperfusion injury
por: Yu, Songzuo, et al.
Publicado: (2021)

miR-101 targeting ZFX suppresses tumor proliferation and metastasis by regulating the MAPK/Erk and Smad pathways in gallbladder carcinoma
por: Bao, Run-Fa, et al.
Publicado: (2016)

Calycosin inhibits breast cancer cell migration and invasion by suppressing EMT via BATF/TGF-β1
por: Zhang, Zhenxia, et al.
Publicado: (2021)

G3BP1 regulates breast cancer cell proliferation and metastasis by modulating PKCζ
por: Liu, Shuang, et al.
Publicado: (2022)

Small Molecule-Based Promotion of PKCα-Mediated β-Catenin Degradation Suppresses the Proliferation of CRT-Positive Cancer Cells
por: Gwak, Jungsug, et al.
Publicado: (2012)

Resveratrol prevents nanoparticles-induced inflammation and oxidative stress via downregulation of PKC-α and NADPH oxidase in lung epithelial A549 cells
por: Hsu, Hung-Te, et al.
Publicado: (2018)

CT45A1 siRNA silencing suppresses the proliferation, metastasis and invasion of lung cancer cells by downregulating the ERK/CREB signaling pathway
por: Tang, Feng, et al.
Publicado: (2017)

Combination therapy of PKCζ and COX-2 inhibitors synergistically suppress melanoma metastasis
por: Zhou, Ping, et al.
Publicado: (2017)

Different Associations of CD45 Isoforms with STAT3, PKC and ERK Regulate IL-6-Induced Proliferation in Myeloma
por: Zheng, Xu, et al.
Publicado: (2015)

Profiling of Hepatocellular Carcinoma Cell Cycle Regulating Genes Targeted by Calycosin
por: Zhang, Dongqing, et al.
Publicado: (2013)

Calycosin attenuates dextran sulfate sodium (DSS)-induced experimental colitis
por: Chao, Liu, et al.
Publicado: (2017)

Pharmaceutical Values of Calycosin: One Type of Flavonoid Isolated from Astragalus
por: Gong, Guowei, et al.
Publicado: (2021)

Research on the interaction of astragaloside IV and calycosin in Astragalus membranaceus with HMGB1
por: Ye, Junyi, et al.
Publicado: (2023)

In vivo and in vitro effects of hyperplasia suppressor gene on the proliferation and apoptosis of lung adenocarcinoma A549 cells
por: Sun, Zhen-Qing, et al.
Publicado: (2018)

Effect of daphnoretin on the proliferation and apoptosis of A549 lung cancer cells in vitro
por: JIANG, HONG-FANG, et al.
Publicado: (2014)

Thrombomodulin regulates monocye differentiation via PKCδ and ERK1/2 pathway in vitro and in atherosclerotic artery
por: Tsai, Chien-Sung, et al.
Publicado: (2016)

Bioinformatics and In Silico Findings Uncover Bio-Targets of Calycosin Against Heart Failure and Diabetes Mellitus
por: Xu, Hongyuan, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_5o5ap0jn2n3bu9hgriofl3pmsb