Cargando…

The Role of DNA Mismatch Repair and Recombination in the Processing of DNA Alkylating Damage in Living Yeast Cells

It is proposed that mismatch repair (MMR) mediates the cytotoxic effects of DNA damaging agents by exerting a futile repair pathway which leads to double strand breaks (DSBs). Previous reports indicate that the sensitivity of cells defective in homologous recombination (HR) to DNA alkylation is redu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Flores-Rozas, Hernan, Jaafar, Lahcen, Xia, Ling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758339/ https://www.ncbi.nlm.nih.gov/pubmed/26900494 http://dx.doi.org/10.4236/abb.2015.66040

Ejemplares similares

Differential contribution of mismatch repair genes in the processing of DNA damage
por: Flores-Rozas, Hernan
Publicado: (2011)

Proteomic analysis of mismatch repair-mediated alkylating agent-induced DNA damage response
por: Chen, Xi, et al.
Publicado: (2013)

Modulation of the DNA-binding activity of Saccharomyces cerevisiae MSH2–MSH6 complex by the high-mobility group protein NHP6A, in vitro
por: Labazi, Mohamed, et al.
Publicado: (2009)

DNA Alkylation Damage by Nitrosamines and Relevant DNA Repair Pathways
por: Fahrer, Jörg, et al.
Publicado: (2023)

Mismatch repair deficiency is associated with resistance to DNA minor groove alkylating agents
por: Colella, G, et al.
Publicado: (1999)

Regulation of DNA damage responses by mismatch repair
por: Zhitkovich, Anatoly
Publicado: (2010)

DNA Damage Induced by Alkylating Agents and Repair Pathways
por: Kondo, Natsuko, et al.
Publicado: (2010)

DNA Mismatch Repair and Oxidative DNA Damage: Implications for Cancer Biology and Treatment
por: Bridge, Gemma, et al.
Publicado: (2014)

Selective alkylation of T–T mismatched DNA using vinyldiaminotriazine–acridine conjugate
por: Onizuka, Kazumitsu, et al.
Publicado: (2018)

DNA repair, recombination, and damage signaling
por: Gartner, Anton, et al.
Publicado: (2021)

Alkylated DNA damage flipping bridges base and nucleotide excision repair
por: Tubbs, Julie L., et al.
Publicado: (2009)

Rapid Identification of Chemoresistance Mechanisms Using Yeast DNA Mismatch Repair Mutants
por: Ojini, Irene, et al.
Publicado: (2015)

Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2–MSH6 complex
por: Banerjee, Sreeparna, et al.
Publicado: (2005)

Cadmium inhibits mismatch repair by blocking the ATPase activity of the MSH2–MSH6 complex
por: Banerjee, Sreeparna, et al.
Publicado: (2005)

Imaging Mismatch Repair and Cellular Responses to DNA Damage in Bacillus subtilis
por: Klocko, Andrew D., et al.
Publicado: (2010)

Mutational spectrum of DNA damage and mismatch repair genes in prostate cancer
por: Bugoye, Fidelis Charles, et al.
Publicado: (2023)

Genome-Wide Analysis of Heteroduplex DNA in Mismatch Repair–Deficient Yeast Cells Reveals Novel Properties of Meiotic Recombination Pathways
por: Martini, Emmanuelle, et al.
Publicado: (2011)

Versatile cell-based assay for measuring DNA alkylation damage and its repair
por: Li, Yong, et al.
Publicado: (2021)

A ‘Semi-Protected Oligonucleotide Recombination’ Assay for DNA Mismatch Repair in vivo Suggests Different Modes of Repair for Lagging Strand Mismatches
por: Josephs, Eric A., et al.
Publicado: (2017)

DNA Mismatch Repair in Eukaryotes and Bacteria
por: Fukui, Kenji
Publicado: (2010)

DNA mismatch repair in the context of chromatin
por: Huang, Yaping, et al.
Publicado: (2020)

DNA mismatch repair in cancer immunotherapy
por: Guan, Junhong, et al.
Publicado: (2023)

DNA mismatch repair protein Mlh1 is required for tetravalent chromium intermediate-induced DNA damage
por: Wakeman, Timothy P., et al.
Publicado: (2017)

Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes
por: Klein, Hannah L, et al.
Publicado: (2019)

Role of Homologous Recombination Genes in Repair of Alkylation Base Damage by Candida albicans
por: Ciudad, Toni, et al.
Publicado: (2018)

Loss of DNA mismatch repair facilitates reactivation of a reporter plasmid damaged by cisplatin
por: Cenni, B, et al.
Publicado: (1999)

Speciation of Genes and Genomes: Conservation of DNA Polymorphism by Barriers to Recombination Raised by Mismatch Repair System
por: Radman, Miroslav
Publicado: (2022)

Correction to: DNA mismatch repair in the context of chromatin
por: Huang, Yaping, et al.
Publicado: (2020)

The detection of alkylation damage in the DNA of human gastrointestinal tissues.
por: Hall, C. N., et al.
Publicado: (1991)

Dual daughter strand incision is processive and increases the efficiency of DNA mismatch repair
por: Hermans, Nicolaas, et al.
Publicado: (2016)

Ligation of newly replicated DNA controls the timing of DNA mismatch repair
por: Reyes, Gloria X., et al.
Publicado: (2021)

Human DNA mismatch repair: coupling of mismatch recognition to strand-specific excision
por: Wang, Huixian, et al.
Publicado: (2007)

Genome-wide maps of alkylation damage, repair, and mutagenesis in yeast reveal mechanisms of mutational heterogeneity
por: Mao, Peng, et al.
Publicado: (2017)

Recruitment of DNA repair synthesis machinery to sites of DNA damage/repair in living human cells
por: Hashiguchi, Kazunari, et al.
Publicado: (2007)

Structure-function relationships governing activity and stability of a DNA alkylation damage repair thermostable protein
por: Perugino, Giuseppe, et al.
Publicado: (2015)

DNA mismatch repair gene mutations in human cancer.
por: Peltomäki, P
Publicado: (1997)

Fluorescence detection of DNA mismatch repair in human cells
por: Ito, Shunsuke, et al.
Publicado: (2018)

Loss of DNA mismatch repair proteins in prostate cancer
por: Sharma, Meenal, et al.
Publicado: (2020)

DNA Mismatch Repair and its Role in Huntington’s Disease
por: Iyer, Ravi R., et al.
Publicado: (2021)

The role of DNA mismatch repair in immunotherapy of human cancer
por: He, Yuchen, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_u43uodiuaqjir3v73u5ppsad03