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Walls talk: Microbial biogeography of homes spanning urbanization
Westernization has propelled changes in urbanization and architecture, altering our exposure to the outdoor environment from that experienced during most of human evolution. These changes might affect the developmental exposure of infants to bacteria, immune development, and human microbiome diversi...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758746/ https://www.ncbi.nlm.nih.gov/pubmed/26933683 http://dx.doi.org/10.1126/sciadv.1501061 |
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author | Ruiz-Calderon, Jean F. Cavallin, Humberto Song, Se Jin Novoselac, Atila Pericchi, Luis R. Hernandez, Jean N. Rios, Rafael Branch, Oralee H. Pereira, Henrique Paulino, Luciana C. Blaser, Martin J. Knight, Rob Dominguez-Bello, Maria G. |
author_facet | Ruiz-Calderon, Jean F. Cavallin, Humberto Song, Se Jin Novoselac, Atila Pericchi, Luis R. Hernandez, Jean N. Rios, Rafael Branch, Oralee H. Pereira, Henrique Paulino, Luciana C. Blaser, Martin J. Knight, Rob Dominguez-Bello, Maria G. |
author_sort | Ruiz-Calderon, Jean F. |
collection | PubMed |
description | Westernization has propelled changes in urbanization and architecture, altering our exposure to the outdoor environment from that experienced during most of human evolution. These changes might affect the developmental exposure of infants to bacteria, immune development, and human microbiome diversity. Contemporary urban humans spend most of their time indoors, and little is known about the microbes associated with different designs of the built environment and their interaction with the human immune system. This study addresses the associations between architectural design and the microbial biogeography of households across a gradient of urbanization in South America. Urbanization was associated with households’ increased isolation from outdoor environments, with additional indoor space isolation by walls. Microbes from house walls and floors segregate by location, and urban indoor walls contain human bacterial markers of space use. Urbanized spaces uniquely increase the content of human-associated microbes—which could increase transmission of potential pathogens—and decrease exposure to the environmental microbes with which humans have coevolved. |
format | Online Article Text |
id | pubmed-4758746 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-47587462016-03-01 Walls talk: Microbial biogeography of homes spanning urbanization Ruiz-Calderon, Jean F. Cavallin, Humberto Song, Se Jin Novoselac, Atila Pericchi, Luis R. Hernandez, Jean N. Rios, Rafael Branch, Oralee H. Pereira, Henrique Paulino, Luciana C. Blaser, Martin J. Knight, Rob Dominguez-Bello, Maria G. Sci Adv Research Articles Westernization has propelled changes in urbanization and architecture, altering our exposure to the outdoor environment from that experienced during most of human evolution. These changes might affect the developmental exposure of infants to bacteria, immune development, and human microbiome diversity. Contemporary urban humans spend most of their time indoors, and little is known about the microbes associated with different designs of the built environment and their interaction with the human immune system. This study addresses the associations between architectural design and the microbial biogeography of households across a gradient of urbanization in South America. Urbanization was associated with households’ increased isolation from outdoor environments, with additional indoor space isolation by walls. Microbes from house walls and floors segregate by location, and urban indoor walls contain human bacterial markers of space use. Urbanized spaces uniquely increase the content of human-associated microbes—which could increase transmission of potential pathogens—and decrease exposure to the environmental microbes with which humans have coevolved. American Association for the Advancement of Science 2016-02-12 /pmc/articles/PMC4758746/ /pubmed/26933683 http://dx.doi.org/10.1126/sciadv.1501061 Text en Copyright © 2016, The Authors http://creativecommons.org/licenses/by-nc/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial license (http://creativecommons.org/licenses/by-nc/4.0/) , which permits use, distribution, and reproduction in any medium, so long as the resultant use is not for commercial advantage and provided the original work is properly cited. |
spellingShingle | Research Articles Ruiz-Calderon, Jean F. Cavallin, Humberto Song, Se Jin Novoselac, Atila Pericchi, Luis R. Hernandez, Jean N. Rios, Rafael Branch, Oralee H. Pereira, Henrique Paulino, Luciana C. Blaser, Martin J. Knight, Rob Dominguez-Bello, Maria G. Walls talk: Microbial biogeography of homes spanning urbanization |
title | Walls talk: Microbial biogeography of homes spanning urbanization |
title_full | Walls talk: Microbial biogeography of homes spanning urbanization |
title_fullStr | Walls talk: Microbial biogeography of homes spanning urbanization |
title_full_unstemmed | Walls talk: Microbial biogeography of homes spanning urbanization |
title_short | Walls talk: Microbial biogeography of homes spanning urbanization |
title_sort | walls talk: microbial biogeography of homes spanning urbanization |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758746/ https://www.ncbi.nlm.nih.gov/pubmed/26933683 http://dx.doi.org/10.1126/sciadv.1501061 |
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