Cargando…

Protective effect of fucoidan from Fucus vesiculosus on liver fibrosis via the TGF-β1/Smad pathway-mediated inhibition of extracellular matrix and autophagy

Liver fibrosis is a dynamic reversible pathological process in the development of chronic liver disease to cirrhosis. However, the current treatments are not administered for a long term due to their various side effects. Autophagy is initiated to decompose damaged or excess organelles, which had be...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Jingjing, Chen, Kan, Li, Sainan, Feng, Jiao, Liu, Tong, Wang, Fan, Zhang, Rong, Xu, Shizan, Zhou, Yuqing, Zhou, Shunfeng, Xia, Yujing, Lu, Jie, Zhou, Yingqun, Guo, Chuanyong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758785/ https://www.ncbi.nlm.nih.gov/pubmed/26929597 http://dx.doi.org/10.2147/DDDT.S98740

Ejemplares similares

Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis
por: Li, Jingjing, et al.
Publicado: (2016)

Fucoidan from Fucus vesiculosus Inhibits Inflammatory Response, Both In Vitro and In Vivo
por: Wang, Lingzhi, et al.
Publicado: (2023)

Biological effects of fucoidan isolated from Fucus vesiculosus on thrombosis and vascular cells
por: Kwak, Kyu-Won, et al.
Publicado: (2010)

Commercial Fucoidans from Fucus vesiculosus Can Be Grouped into Antiadipogenic and Adipogenic Agents
por: Oliveira, Ruth Medeiros, et al.
Publicado: (2018)

Quercetin prevents hepatic fibrosis by inhibiting hepatic stellate cell activation and reducing autophagy via the TGF-β1/Smads and PI3K/Akt pathways
por: Wu, Liwei, et al.
Publicado: (2017)

Physicochemical and Biological Characterization of Fucoidan from Fucus vesiculosus Purified by Dye Affinity Chromatography
por: Zayed, Ahmed, et al.
Publicado: (2016)

Pharmacokinetic and Tissue Distribution of Fucoidan from Fucus vesiculosus after Oral Administration to Rats
por: Pozharitskaya, Olga N., et al.
Publicado: (2018)

Mechanisms of Bioactivities of Fucoidan from the Brown Seaweed Fucus vesiculosus L. of the Barents Sea
por: Pozharitskaya, Olga N., et al.
Publicado: (2020)

Antibacterial Properties of Fucoidans from the Brown Algae Fucus vesiculosus L. of the Barents Sea
por: Ayrapetyan, Olga N., et al.
Publicado: (2021)

Fucoidans of Brown Algae: Comparison of Sulfated Polysaccharides from Fucus vesiculosus and Ascophyllum nodosum
por: Usov, Anatolii I., et al.
Publicado: (2022)

Bioactivity of Fucoidan-Rich Extracts from Fucus vesiculosus against Rotavirus and Foodborne Pathogens
por: Graikini, Dimitra, et al.
Publicado: (2023)

Fucoidan from Fucus vesiculosus: Evaluation of the Impact of the Sulphate Content on Nanoparticle Production and Cell Toxicity
por: Flórez-Fernández, Noelia, et al.
Publicado: (2023)

Fucoidan from Fucus vesiculosus suppresses hepatitis B virus replication by enhancing extracellular signal-regulated Kinase activation
por: Li, Huifang, et al.
Publicado: (2017)

Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer Treatment
por: Mathew, Lata, et al.
Publicado: (2016)

Effects of fucoidan from Fucus vesiculosus in reducing symptoms of osteoarthritis: a randomized placebo-controlled trial
por: Myers, Stephen P, et al.
Publicado: (2016)

Preclinical Evaluation of Safety of Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus for Use in Cancer Treatment
por: Bovet, Luc, et al.
Publicado: (2019)

The Reduction of Adipose Tissue by Fucus Vesiculosus
Publicado: (1907)

Shikonin Attenuates Concanavalin A-Induced Acute Liver Injury in Mice via Inhibition of the JNK Pathway
por: Liu, Tong, et al.
Publicado: (2016)

Metformin and Diammonium Glycyrrhizinate Enteric-Coated Capsule versus Metformin Alone versus Diammonium Glycyrrhizinate Enteric-Coated Capsule Alone in Patients with Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus
por: Zhang, Rong, et al.
Publicado: (2017)

Anticancer, Enhanced Antibacterial, and Free Radical Scavenging Potential of Fucoidan- (Fucus vesiculosus Source) Mediated Silver Nanoparticles
por: Rajeshkumar, S., et al.
Publicado: (2021)

Salidroside ameliorates autophagy and activation of hepatic stellate cells in mice via NF-κB and TGF-β1/Smad3 pathways
por: Feng, Jiao, et al.
Publicado: (2018)

In vitro and in vivo study of epigallocatechin-3-gallate-induced apoptosis in aerobic glycolytic hepatocellular carcinoma cells involving inhibition of phosphofructokinase activity
por: Li, Sainan, et al.
Publicado: (2016)

Cerebral Hemodynamics and Cognitive Function in Cirrhotic Patients with Hepatic Encephalopathy
por: Zhou, Yuqing, et al.
Publicado: (2016)

Rhenium uptake and distribution in phaeophyceae macroalgae, Fucus vesiculosus
por: Racionero-Gómez, B., et al.
Publicado: (2016)

Polymorphic microsatellite markers in the brown seaweed Fucus vesiculosus
por: Candeias, Rui, et al.
Publicado: (2015)

Microwave-Assisted Extraction of Phlorotannins from Fucus vesiculosus
por: Amarante, Sónia J., et al.
Publicado: (2020)

Water Extraction Kinetics of Bioactive Compounds of Fucus vesiculosus
por: Ferreira, Ricardo M., et al.
Publicado: (2019)

Hypertriglyceridemia treated with Fucus vesiculosus – A case series
por: Ponnam, Hima Bindu, et al.
Publicado: (2021)

Evaluation Fucoidan Extracts From Undaria pinnatifida and Fucus vesiculosus in Combination With Anticancer Drugs in Human Cancer Orthotopic Mouse Models
por: Burney, Maryam, et al.
Publicado: (2017)

Epigallocatechin-3-gallate attenuates apoptosis and autophagy in concanavalin A-induced hepatitis by inhibiting BNIP3
por: Li, Sainan, et al.
Publicado: (2016)

Seasonal Variations in Surface Metabolite Composition of Fucus vesiculosus and Fucus serratus from the Baltic Sea
por: Rickert, Esther, et al.
Publicado: (2016)

Anti-Metabolic Syndrome Effects of Fucoidan from Fucus vesiculosus via Reactive Oxygen Species-Mediated Regulation of JNK, Akt, and AMPK Signaling
por: Wang, Xueliang, et al.
Publicado: (2019)

Quercetin Pretreatment Attenuates Hepatic Ischemia Reperfusion-Induced Apoptosis and Autophagy by Inhibiting ERK/NF-κB Pathway
por: Wu, Liwei, et al.
Publicado: (2017)

Sex-biased gene expression in the brown alga Fucus vesiculosus
por: Martins, Maria João F, et al.
Publicado: (2013)

Gene regulatory response to hyposalinity in the brown seaweed Fucus vesiculosus
por: Rugiu, Luca, et al.
Publicado: (2020)

Fucoidan from Fucus vesiculosus Protects against Alcohol-Induced Liver Damage by Modulating Inflammatory Mediators in Mice and HepG2 Cells
por: Lim, Jung Dae, et al.
Publicado: (2015)

Fucoidan Derived from Fucus vesiculosus Inhibits the Development of Human Ovarian Cancer via the Disturbance of Calcium Homeostasis, Endoplasmic Reticulum Stress, and Angiogenesis
por: Bae, Hyocheol, et al.
Publicado: (2020)

Methyl jasmonate leads to necrosis and apoptosis in hepatocellular carcinoma cells via inhibition of glycolysis and represses tumor growth in mice
por: Li, Jingjing, et al.
Publicado: (2017)

TGF‐β/Smad and JAK/STAT pathways are involved in the anti‐fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis
por: Xu, Shizan, et al.
Publicado: (2020)

Bergenin Attenuates Hepatic Fibrosis by Regulating Autophagy Mediated by the PPAR-γ/TGF-β Pathway
por: Xia, Yujing, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qe63f63cu5sig29pbf79a3vg00