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Impaired mitochondrial biogenesis is a common feature to myocardial hypertrophy and end-stage ischemic heart failure

Mitochondrial (mt) DNA depletion and oxidative mtDNA damage have been implicated in the process of pathological cardiac remodeling. Whether these features are present in the early phase of maladaptive cardiac remodeling, that is, during compensated cardiac hypertrophy, is still unknown. We compared...

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Detalles Bibliográficos
Autores principales: Pisano, Annalinda, Cerbelli, Bruna, Perli, Elena, Pelullo, Maria, Bargelli, Valentina, Preziuso, Carmela, Mancini, Massimiliano, He, Langping, Bates, Matthew GD, Lucena, Joaquin R, Della Monica, Paola Lilla, Familiari, Giuseppe, Petrozza, Vincenzo, Nediani, Chiara, Taylor, Robert W, d’Amati, Giulia, Giordano, Carla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Pub. Co 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758811/
https://www.ncbi.nlm.nih.gov/pubmed/26764143
http://dx.doi.org/10.1016/j.carpath.2015.09.009