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pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation

Plasmacytoid dendritic cells (pDCs) exhibit both innate and adaptive functions. In particular they are the main source of type I IFNs and directly impact T cell responses through antigen presentation. We have previously demonstrated that during experimental autoimmune encephalomyelitis (EAE) initiat...

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Detalles Bibliográficos
Autores principales: Duraes, Fernanda V., Lippens, Carla, Steinbach, Karin, Dubrot, Juan, Brighouse, Dale, Bendriss-Vermare, Nathalie, Issazadeh-Navikas, Shohreh, Merkler, Doron, Hugues, Stephanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758828/
https://www.ncbi.nlm.nih.gov/pubmed/26341385
http://dx.doi.org/10.1016/j.jaut.2015.08.014