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pDC therapy induces recovery from EAE by recruiting endogenous pDC to sites of CNS inflammation
Plasmacytoid dendritic cells (pDCs) exhibit both innate and adaptive functions. In particular they are the main source of type I IFNs and directly impact T cell responses through antigen presentation. We have previously demonstrated that during experimental autoimmune encephalomyelitis (EAE) initiat...
Autores principales: | Duraes, Fernanda V., Lippens, Carla, Steinbach, Karin, Dubrot, Juan, Brighouse, Dale, Bendriss-Vermare, Nathalie, Issazadeh-Navikas, Shohreh, Merkler, Doron, Hugues, Stephanie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4758828/ https://www.ncbi.nlm.nih.gov/pubmed/26341385 http://dx.doi.org/10.1016/j.jaut.2015.08.014 |
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