Effects of the potential lithium-mimetic, ebselen, on brain neurochemistry: a magnetic resonance spectroscopy study at 7 tesla

RATIONALE: Lithium is an effective treatment for bipolar disorder, but safety issues complicate its clinical use. The antioxidant drug, ebselen, may be a possible lithium-mimetic based on its ability to inhibit inositol monophosphatase (IMPase), an action which it shares with lithium. OBJECTIVES: Ou...

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Detalles Bibliográficos
Autores principales: Masaki, Charles, Sharpley, Ann L., Godlewska, Beata R., Berrington, Adam, Hashimoto, Tasuku, Singh, Nisha, Vasudevan, Sridhar R., Emir, Uzay E., Churchill, Grant C., Cowen, Philip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759215/
https://www.ncbi.nlm.nih.gov/pubmed/26758281
http://dx.doi.org/10.1007/s00213-015-4189-2

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