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Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation

Bone continuously undergoes remodeling by a tightly regulated process that involves osteoblast differentiation from Mesenchymal Stem Cells (MSC). However, commitment of MSC to osteoblastic lineage is a poorly understood process. Chromatin organization functions as a molecular gatekeeper of DNA funct...

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Detalles Bibliográficos
Autores principales: Thompson, Bethtrice, Varticovski, Lyuba, Baek, Songjoon, Hager, Gordon L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759368/
https://www.ncbi.nlm.nih.gov/pubmed/26890492
http://dx.doi.org/10.1371/journal.pone.0148619