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Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation
Bone continuously undergoes remodeling by a tightly regulated process that involves osteoblast differentiation from Mesenchymal Stem Cells (MSC). However, commitment of MSC to osteoblastic lineage is a poorly understood process. Chromatin organization functions as a molecular gatekeeper of DNA funct...
Autores principales: | Thompson, Bethtrice, Varticovski, Lyuba, Baek, Songjoon, Hager, Gordon L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759368/ https://www.ncbi.nlm.nih.gov/pubmed/26890492 http://dx.doi.org/10.1371/journal.pone.0148619 |
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