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Hirsutella sinensis Attenuates Aristolochic Acid-Induced Renal Tubular Epithelial-Mesenchymal Transition by Inhibiting TGF-β1 and Snail Expression

OBJECTIVE: To investigate the inhibitory effect of Hirsutella sinensis (HS) on epithelial-mesenchymal transition (EMT) of renal tubular epithelial cells induced by aristolochic acid (AA) and its possible mechanism. METHODS: 18 male Sprague-Dawley rats were randomly and equally divided into the follo...

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Detalles Bibliográficos
Autores principales: Xu, Xiao-yi, Chai, Jing-jing, Chen, Yi-pu, Rui, Hong-liang, Wang, Yan-yan, Dong, Hong-rui, Man, Yu-lin, Cheng, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759455/
https://www.ncbi.nlm.nih.gov/pubmed/26890569
http://dx.doi.org/10.1371/journal.pone.0149242

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