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Corneal xanthogranuloma in association with multiple endocrine neoplasia 1: A clinicopathologic case report and review of the literature

Juvenile xanthogranuloma (JXG) is a benign inflammatory condition of uncertain pathogenesis. It is characterized by skin and ocular involvement – typically in the iris – in children. It has been reported in older age groups and has been also observed to involve other ocular structures such as the co...

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Detalles Bibliográficos
Autores principales: Alkatan, Hind M., Al-Rajhi, Ali A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759509/
https://www.ncbi.nlm.nih.gov/pubmed/26949359
http://dx.doi.org/10.1016/j.sjopt.2015.11.006
Descripción
Sumario:Juvenile xanthogranuloma (JXG) is a benign inflammatory condition of uncertain pathogenesis. It is characterized by skin and ocular involvement – typically in the iris – in children. It has been reported in older age groups and has been also observed to involve other ocular structures such as the cornea and conjunctiva. In this case report, we are presenting an extensive right eye corneal lesion in a 43-year old male which showed the typical histopathological feature of JXG and in association with multiple endocrine neoplasia (type 1). Similar cases in the English-language literature have been also reviewed.