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Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China

Anal human papillomavirus (HPV) infection, which is linked to anal warts and anal cancer, is common among men who have sex with men (MSM), especially among those HIV positives. MSM aged 18 years or older were recruited from mainland China. Blood and anal cytologic samples were collected for HIV-1 se...

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Autores principales: Li, Xiangwei, Li, Mufei, Yang, Yu, Zhong, Xiang, Feng, Boxuan, Xin, Henan, Li, Zhen, Jin, Qi, Gao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759533/
https://www.ncbi.nlm.nih.gov/pubmed/26892938
http://dx.doi.org/10.1038/srep21368
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author Li, Xiangwei
Li, Mufei
Yang, Yu
Zhong, Xiang
Feng, Boxuan
Xin, Henan
Li, Zhen
Jin, Qi
Gao, Lei
author_facet Li, Xiangwei
Li, Mufei
Yang, Yu
Zhong, Xiang
Feng, Boxuan
Xin, Henan
Li, Zhen
Jin, Qi
Gao, Lei
author_sort Li, Xiangwei
collection PubMed
description Anal human papillomavirus (HPV) infection, which is linked to anal warts and anal cancer, is common among men who have sex with men (MSM), especially among those HIV positives. MSM aged 18 years or older were recruited from mainland China. Blood and anal cytologic samples were collected for HIV-1 serological test and HPV genotyping. A total of 889 eligible participations were included. The genotyping results of HPV were available for 822 participants (92.46%), 65.32% of which were positive for the targeted 37 HPV types. Prevalence of infection with any type of HPV was higher among HIV-infected participants (82.69%) as compared to HIV-uninfected participants (62.81%) (p < 0.01). HPV06 (15.45%), HPV18(13.50%), HPV16 (11.44%), and HPV11 (10.71%) were the most frequent types identified in the study population. Ever had paid sex with man was found to be independent predictor for HPV positivity with an adjusted odds ratios (OR) of 2.34 (1.16–4.74). Anal HPV positivity was observed to be independently associated with HIV infection with an adjusted OR of 3.03 (1.76–5.21) in the study population. In conclusion, the prevalence of anal HPV infection was observed to be common among MSM from mainland China, and it was significantly associated with the status of HIV infection.
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spelling pubmed-47595332016-02-26 Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China Li, Xiangwei Li, Mufei Yang, Yu Zhong, Xiang Feng, Boxuan Xin, Henan Li, Zhen Jin, Qi Gao, Lei Sci Rep Article Anal human papillomavirus (HPV) infection, which is linked to anal warts and anal cancer, is common among men who have sex with men (MSM), especially among those HIV positives. MSM aged 18 years or older were recruited from mainland China. Blood and anal cytologic samples were collected for HIV-1 serological test and HPV genotyping. A total of 889 eligible participations were included. The genotyping results of HPV were available for 822 participants (92.46%), 65.32% of which were positive for the targeted 37 HPV types. Prevalence of infection with any type of HPV was higher among HIV-infected participants (82.69%) as compared to HIV-uninfected participants (62.81%) (p < 0.01). HPV06 (15.45%), HPV18(13.50%), HPV16 (11.44%), and HPV11 (10.71%) were the most frequent types identified in the study population. Ever had paid sex with man was found to be independent predictor for HPV positivity with an adjusted odds ratios (OR) of 2.34 (1.16–4.74). Anal HPV positivity was observed to be independently associated with HIV infection with an adjusted OR of 3.03 (1.76–5.21) in the study population. In conclusion, the prevalence of anal HPV infection was observed to be common among MSM from mainland China, and it was significantly associated with the status of HIV infection. Nature Publishing Group 2016-02-19 /pmc/articles/PMC4759533/ /pubmed/26892938 http://dx.doi.org/10.1038/srep21368 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Li, Xiangwei
Li, Mufei
Yang, Yu
Zhong, Xiang
Feng, Boxuan
Xin, Henan
Li, Zhen
Jin, Qi
Gao, Lei
Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China
title Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China
title_full Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China
title_fullStr Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China
title_full_unstemmed Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China
title_short Anal HPV/HIV co-infection among Men Who Have Sex with Men: a cross-sectional survey from three cities in China
title_sort anal hpv/hiv co-infection among men who have sex with men: a cross-sectional survey from three cities in china
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759533/
https://www.ncbi.nlm.nih.gov/pubmed/26892938
http://dx.doi.org/10.1038/srep21368
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