Progranulin inhibits expression and release of chemokines CXCL9 and CXCL10 in a TNFR1 dependent manner

Progranulin (PGRN), a pleiotrophic growth factor, is known to play an important role in the maintenance and regulation of the homeostatic dynamics of normal tissue development, proliferation, regeneration, and host-defense. PGRN also has potent anti-inflammatory functionality, and deregulated PGRN i...

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Detalles Bibliográficos
Autores principales: Mundra, Jyoti Joshi, Jian, Jinlong, Bhagat, Priyal, Liu, Chuan-ju
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759551/
https://www.ncbi.nlm.nih.gov/pubmed/26892362
http://dx.doi.org/10.1038/srep21115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759551/
https://www.ncbi.nlm.nih.gov/pubmed/26892362
http://dx.doi.org/10.1038/srep21115

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