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Ultrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell Responses
Ultrasensitivity allows filtering weak activating signals and responding emphatically to small changes in stronger stimuli. In the presence of positive feedback loops, ultrasensitivity enables the existence of bistability, which convert graded stimuli into switch-like, sometimes irreversible, respon...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759566/ https://www.ncbi.nlm.nih.gov/pubmed/26925064 http://dx.doi.org/10.3389/fimmu.2016.00059 |