A DNA aptamer recognising a malaria protein biomarker can function as part of a DNA origami assembly

DNA aptamers have potential for disease diagnosis and as therapeutics, particularly when interfaced with programmable molecular technology. Here we have combined DNA aptamers specific for the malaria biomarker Plasmodium falciparum lactate dehydrogenase (PfLDH) with a DNA origami scaffold. Twelve ap...

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Detalles Bibliográficos
Autores principales: Godonoga, Maia, Lin, Ting-Yu, Oshima, Azusa, Sumitomo, Koji, Tang, Marco S. L., Cheung, Yee-Wai, Kinghorn, Andrew B., Dirkzwager, Roderick M., Zhou, Cunshan, Kuzuya, Akinori, Tanner, Julian A., Heddle, Jonathan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759581/
https://www.ncbi.nlm.nih.gov/pubmed/26891622
http://dx.doi.org/10.1038/srep21266

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