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Activation of the TGFβ pathway impairs endothelial to haematopoietic transition
The endothelial to haematopoietic transition (EHT) is a key developmental process where a drastic change of endothelial cell morphology leads to the formation of blood stem and progenitor cells during embryogenesis. As TGFβ signalling triggers a similar event during embryonic development called epit...
Autores principales: | Vargel, Özge, Zhang, Yang, Kosim, Kinga, Ganter, Kerstin, Foehr, Sophia, Mardenborough, Yannicka, Shvartsman, Maya, Enright, Anton J., Krijgsveld, Jeroen, Lancrin, Christophe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4759586/ https://www.ncbi.nlm.nih.gov/pubmed/26891705 http://dx.doi.org/10.1038/srep21518 |
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